Which copper transport protein migrates as an alpha2-globulin?

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Multiple Choice

Which copper transport protein migrates as an alpha2-globulin?

Explanation:
Copper in the blood is carried mainly by ceruloplasmin, a copper-containing enzyme produced by the liver. Ceruloplasmin binds most of the circulating copper and provides ferroxidase activity. When serum proteins are separated by electrophoresis, ceruloplasmin appears in the alpha-2 globulin region due to its size and charge, so it migrates there. Therefore, the copper transport protein that migrates as an alpha-2 globulin is ceruloplasmin. For context, haptoglobin binds free hemoglobin and is not a copper transporter; transferrin transports iron and is in the beta globulin region; fibrinogen is a clotting factor and is not a copper transporter.

Copper in the blood is carried mainly by ceruloplasmin, a copper-containing enzyme produced by the liver. Ceruloplasmin binds most of the circulating copper and provides ferroxidase activity. When serum proteins are separated by electrophoresis, ceruloplasmin appears in the alpha-2 globulin region due to its size and charge, so it migrates there. Therefore, the copper transport protein that migrates as an alpha-2 globulin is ceruloplasmin.

For context, haptoglobin binds free hemoglobin and is not a copper transporter; transferrin transports iron and is in the beta globulin region; fibrinogen is a clotting factor and is not a copper transporter.

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