The secretion of which substance is controlled by growth hormone?

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Enhance your knowledge with the Ciulla Clinical Chemistry Test. Study with interactive quizzes, featuring flashcards and multiple-choice questions. Each question offers hints and explanations for better understanding. Prepare effectively and excel in your exam!

Multiple Choice

The secretion of which substance is controlled by growth hormone?

Explanation:
Growth hormone exerts its growth-promoting effects largely by stimulating the liver and other tissues to produce somatomedins, especially IGF-1 (somatomedin C). These mediators carry out the actions of GH on bones and cartilage, promoting growth. So, the substance whose secretion is driven by growth hormone is somatomedin. In contrast, a hormone that would increase GH release is growth hormone–releasing hormone, a hormone that stimulates ACTH is corticotropin-releasing hormone, and somatostatin actually inhibits GH release.

Growth hormone exerts its growth-promoting effects largely by stimulating the liver and other tissues to produce somatomedins, especially IGF-1 (somatomedin C). These mediators carry out the actions of GH on bones and cartilage, promoting growth. So, the substance whose secretion is driven by growth hormone is somatomedin. In contrast, a hormone that would increase GH release is growth hormone–releasing hormone, a hormone that stimulates ACTH is corticotropin-releasing hormone, and somatostatin actually inhibits GH release.

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