Primary aldosteronism results from a tumor of the adrenal cortex. How would the extracellular fluid be affected?

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Enhance your knowledge with the Ciulla Clinical Chemistry Test. Study with interactive quizzes, featuring flashcards and multiple-choice questions. Each question offers hints and explanations for better understanding. Prepare effectively and excel in your exam!

Multiple Choice

Primary aldosteronism results from a tumor of the adrenal cortex. How would the extracellular fluid be affected?

Explanation:
Excess aldosterone from an adrenal cortical tumor drives sodium reabsorption in the kidney and increases potassium excretion. Water follows sodium, so the extracellular fluid volume expands. The combined effect is more sodium in the extracellular space and less potassium due to the enhanced renal loss. So the extracellular fluid would have increased sodium and decreased potassium.

Excess aldosterone from an adrenal cortical tumor drives sodium reabsorption in the kidney and increases potassium excretion. Water follows sodium, so the extracellular fluid volume expands. The combined effect is more sodium in the extracellular space and less potassium due to the enhanced renal loss. So the extracellular fluid would have increased sodium and decreased potassium.

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