Not characteristic of multiple myeloma?

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Enhance your knowledge with the Ciulla Clinical Chemistry Test. Study with interactive quizzes, featuring flashcards and multiple-choice questions. Each question offers hints and explanations for better understanding. Prepare effectively and excel in your exam!

Multiple Choice

Not characteristic of multiple myeloma?

Explanation:
In multiple myeloma, malignant plasma cells produce a single type of immunoglobulin, leading to a monoclonal gammopathy. This shows up as an M-spike on serum protein electrophoresis and is accompanied by an increased globulin fraction (hyperglobulinemia) due to excess monoclonal immunoglobulin. Bone involvement from the malignancy causes bone resorption and hypercalcemia. Albumin, however, is not elevated in this disease; it is typically normal or reduced, which lowers the albumin/globulin ratio. Therefore, hyperalbuminemia is not a characteristic feature of multiple myeloma.

In multiple myeloma, malignant plasma cells produce a single type of immunoglobulin, leading to a monoclonal gammopathy. This shows up as an M-spike on serum protein electrophoresis and is accompanied by an increased globulin fraction (hyperglobulinemia) due to excess monoclonal immunoglobulin. Bone involvement from the malignancy causes bone resorption and hypercalcemia. Albumin, however, is not elevated in this disease; it is typically normal or reduced, which lowers the albumin/globulin ratio. Therefore, hyperalbuminemia is not a characteristic feature of multiple myeloma.

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