In a patient suspected of having pheochromocytoma, measurement of which metabolite would be most useful?

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Enhance your knowledge with the Ciulla Clinical Chemistry Test. Study with interactive quizzes, featuring flashcards and multiple-choice questions. Each question offers hints and explanations for better understanding. Prepare effectively and excel in your exam!

Multiple Choice

In a patient suspected of having pheochromocytoma, measurement of which metabolite would be most useful?

In pheochromocytoma, the tumor metabolizes produced catecholamines into metanephrines inside the tumor cells, so these metabolites are generated continuously and show up in the blood or urine even if catecholamine release is episodic. That makes metanephrine testing, especially plasma free metanephrines or urinary fractionated metanephrines, the most sensitive and reliable marker for detecting the tumor.

Other metabolites mentioned don’t fit this context: homovanillic acid is a dopamine metabolite used less commonly for this purpose, 5-hydroxyindoleacetic acid tracks serotonin metabolism and is used for carcinoid tumors, and homogentisic acid is involved in alkaptonuria and not pheochromocytoma.

In a patient suspected of having pheochromocytoma, measurement of which metabolite would be most useful?

Enhance your knowledge with the Ciulla Clinical Chemistry Test. Study with interactive quizzes, featuring flashcards and multiple-choice questions. Each question offers hints and explanations for better understanding. Prepare effectively and excel in your exam!

In a patient suspected of having pheochromocytoma, measurement of which metabolite would be most useful?

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