Given sodium 142 mmol/L, glucose 130 mg/dL, and urea nitrogen 18 mg/dL, the calculated plasma osmolality is approximately:

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Enhance your knowledge with the Ciulla Clinical Chemistry Test. Study with interactive quizzes, featuring flashcards and multiple-choice questions. Each question offers hints and explanations for better understanding. Prepare effectively and excel in your exam!

Multiple Choice

Given sodium 142 mmol/L, glucose 130 mg/dL, and urea nitrogen 18 mg/dL, the calculated plasma osmolality is approximately:

Calculated plasma osmolality is driven by the major osmoles in serum: sodium (counted as 2 Na+ to reflect accompanying anions), glucose, and urea nitrogen. The standard equation is Osm = 2 × Na + glucose/18 + BUN/2.8, where concentrations are in mmol/L for Na, and mg/dL for glucose and BUN.

Plugging in the values: 2 × 142 = 284; glucose term 130/18 ≈ 7.22; BUN term 18/2.8 ≈ 6.43. Adding them gives 284 + 7.22 + 6.43 ≈ 297.65, about 298 mOsm/kg.

This is an approximate value because the formula ignores small contributions from other solutes and from measurement rounding, but it closely matches the given answer.

Given sodium 142 mmol/L, glucose 130 mg/dL, and urea nitrogen 18 mg/dL, the calculated plasma osmolality is approximately:

Enhance your knowledge with the Ciulla Clinical Chemistry Test. Study with interactive quizzes, featuring flashcards and multiple-choice questions. Each question offers hints and explanations for better understanding. Prepare effectively and excel in your exam!

Given sodium 142 mmol/L, glucose 130 mg/dL, and urea nitrogen 18 mg/dL, the calculated plasma osmolality is approximately:

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