Given a total cholesterol of 300 mg/dL, HDL of 50 mg/dL, and triglycerides of 200 mg/dL, what is the calculated LDL cholesterol?

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Multiple Choice

Given a total cholesterol of 300 mg/dL, HDL of 50 mg/dL, and triglycerides of 200 mg/dL, what is the calculated LDL cholesterol?

Explanation:
Friedewald equation is used to estimate LDL cholesterol when triglycerides are not extremely high and the blood sample is fasting. The formula is LDL-C = Total cholesterol – HDL-C – (Triglycerides ÷ 5). Plugging in the numbers: triglycerides ÷ 5 = 200 ÷ 5 = 40. Then LDL-C = 300 – 50 – 40 = 210 mg/dL. This result, 210 mg/dL, is the value you get from the calculation, so it matches the correct choice. Remember, this method works best when triglycerides are under about 400 mg/dL; if triglycerides are higher or the sample isn’t fasting, a direct LDL measurement is preferred.

Friedewald equation is used to estimate LDL cholesterol when triglycerides are not extremely high and the blood sample is fasting. The formula is LDL-C = Total cholesterol – HDL-C – (Triglycerides ÷ 5).

Plugging in the numbers: triglycerides ÷ 5 = 200 ÷ 5 = 40. Then LDL-C = 300 – 50 – 40 = 210 mg/dL.

This result, 210 mg/dL, is the value you get from the calculation, so it matches the correct choice. Remember, this method works best when triglycerides are under about 400 mg/dL; if triglycerides are higher or the sample isn’t fasting, a direct LDL measurement is preferred.

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