Exposure to organophosphate insecticides inhibits which serum enzyme?

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Multiple Choice

Exposure to organophosphate insecticides inhibits which serum enzyme?

Explanation:
Organophosphate insecticides inhibit acetylcholinesterase, the enzyme that breaks down acetylcholine at nerve endings and synapses. When this enzyme is blocked, acetylcholine accumulates, causing overstimulation of cholinergic receptors and the typical symptoms of poisoning. In the blood, this activity is referred to as cholinesterase (often the plasma or butyrylcholinesterase form). The other enzymes listed—lipase, creatine kinase, and alkaline phosphatase—don’t participate in acetylcholine breakdown and aren’t the targets of organophosphate inhibition. So the serum enzyme inhibited by organophosphate exposure is cholinesterase.

Organophosphate insecticides inhibit acetylcholinesterase, the enzyme that breaks down acetylcholine at nerve endings and synapses. When this enzyme is blocked, acetylcholine accumulates, causing overstimulation of cholinergic receptors and the typical symptoms of poisoning. In the blood, this activity is referred to as cholinesterase (often the plasma or butyrylcholinesterase form). The other enzymes listed—lipase, creatine kinase, and alkaline phosphatase—don’t participate in acetylcholine breakdown and aren’t the targets of organophosphate inhibition. So the serum enzyme inhibited by organophosphate exposure is cholinesterase.

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